Sian Cain 

Sam Neill announces he is cancer-free after taking part in Australian clinical trial: ‘I’m very, very excited’

Jurassic Park actor is advocating for CAR T-cell therapy, which he underwent as part of a clinical trial, to be rolled out for blood cancer patients across Australia
  
  

Sam Neill pictured in Los Angeles in 2024
Sam Neill in Los Angeles in 2024. The actor has announced he is now cancer-free after undergoing CAR T-cell therapy, a treatment he sought after chemo stopped working. Photograph: Richard Shotwell/Invision/AP

Sam Neill has announced he is now cancer-free after undergoing a new treatment when chemotherapy stopped working on his stage-three blood cancer.

The Jurassic Park actor made the announcement on Australian broadcaster 7News while advocating for CAR T-cell therapy – a form of cancer immunotherapy which he underwent as part of a clinical trial – to be rolled out for blood cancer patients across Australia.

Neill first revealed that he was being treated for stage-three angioimmunoblastic T-cell lymphoma in his 2023 memoir, Did I Ever Tell You This? When the book was published, the actor was taking a new chemotherapy drug monthly to keep the cancer at bay, telling the Guardian: “I’m not afraid to die, but it would annoy me.”

“I’ve been living with a particular type of lymphoma for about five years and I was on chemotherapy, [which is] pretty miserable business but it was keeping me alive,” Neill told 7News.

But when chemotherapy stopped working, he said: “I was at a loss and it looked like I was on the way out – which wasn’t ideal obviously.”

Neill then took part in a CAR T-cell therapy clinical trial that is focused on his type of lymphoma in Australia.

“I’ve just had a scan just now and there is no cancer in my body, that’s an extraordinary thing,” Neill said. “I’m very, very excited that this can happen.”

He added: “It’s time I did another movie.”

CAR T-cell therapy is currently only available under Australia’s public health system for certain cancers at certain hospitals; privately, the treatment currently costs upwards of A$600,000 (£320,000, US$430,000) per patient in Australia.

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The 78-year-old actor was speaking as part of a campaign to ask Australia’s state and federal governments to expand the availability of CAR T-cell therapy for more cancer patients, with the help of not-for-profit blood cancer foundation Snowdome.

Known as CAR (chimeric antigen receptor) T-cell therapy, the treatment involves taking T-cells, a type of white blood cell, from a patient and genetically engineering them to target and kill cancer cells. These modified T-cells are grown in a laboratory and then infused back into the patient.

CAR T-cell therapy has proved particularly successful in treating certain types of blood cancers. Response rates have been less encouraging in solid tumours, with long-term outcomes unclear. However, in 2025, US researchers revealed a woman who had been treated with CAR T-cell therapy as a child for neuroblastoma, a type of solid tumour, had remained cancer-free for 18 years.

Neill thanked the scientists who helped him, writing on social media, “I am still processing this miraculous information. But of course it is not a miracle, it is science at its best. And a lot of people who care deeply about their work and their patients. I am immensely grateful.

“Treatments like this – CAR-T therapies and others coming through in a rapidly changing medical world – I hope to be available to everyone who needs them in Australia and NZ (and worldwide).

“This is what I am advocating, along with The Snowdome Foundation, to push for exactly that.”

 

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